The Common Ancestry Thread

by cantleave 271 Replies latest members adult

  • cantleave
    cantleave

    As has been stated a number of times on this this it is assumed by evolutionary biologists that all life on Earth emerged from a single common ancestor. Charles Darwin was one of the first scientists to propose there may be a common ancestor for all life on this planet. That plants & animals, bacteria and archaea (single-celled organisms, similar in size to bacteria but different in molecular organization, the third domain of life) are all related, has given rise to a great deal of scepticism.

    Universal common descent is an extremely difficult hypothesis to prove. Even demonstrating a common ancestor between various vertebrates or types of plants is difficult. We have to look at the fossil record, morphological analysis of living organisms and the genetic evidence that exists in every cell of every living organism to find this.

    But to find proof that all living things have a universal common ancestor is magnitudes more complex and difficult. A letter published in the May 13 2010 issue of Nature, written by Douglas Theobald, assistant professor of biochemistry of Brandeis University (Waltham MA), gives us an idea of how these types of problems are solved. His paper provided convincing demonstration of universal common descent using statistical analysis techniques on the amino acid sequences in 23 universally conserved proteins across the three major divisions of life, but which have minor species-specific differences. Using advanced statistical modelling to replicate various relational and evolutionary models, He calculated that descent from one ancestor was 102,860 times more likely than descent from a number of ancestors.

    What is interesting about this, is it demonstrates the predictability of the evolutionary model, even with a purely mathematical interegation. Whatever method of evaluation is chosen to test a a prediction, whether it be the study of fossils, the physical traits of an organism, or an analysis of DNA sequences, the model works. This is can be compared to sending people to the moon or a probe to Mars. If the h eliocentric theory of the solar system and the theory general relativity were wrong these achievements would be impossible. Likewise, it is the same with much of the work we are describing on this thread, if the theory of evolution was not robust, the predictions would be wrong. Biologists are not fitting evidence to their theory, as has been suggested above, the theory allows them to make predictions and then develop methodogies to test them.

  • cofty
    cofty

    Back home and no longer on my stupid phone.

    Cofty, are you going to cover the misunderstanding there has been a radical shift in the thinking on "junk" dna? - Bohm

    Bumping this for Bohm...

    I'm going to post some more about comparable DNA sequences and Cytochrome C later.

  • PSacramento
    PSacramento

    A couple of articles on Encode and "junk" DNA:

    http://biologos.org/blog/series/decoding-encode-series

  • EntirelyPossible
    EntirelyPossible

    From http://www.sciencedaily.com/releases/2013/01/130107100057.htm .....

    Jan. 7, 2013 — Research findings from the University of North Carolina School of Medicine are shining a light on an important regulatory role performed by the so-called dark matter, or "junk DNA," within each of our genes.

    The new study reveals snippets of information contained in dark matter that can alter the way a gene is assembled.

    "These small sequences of genetic information tell the gene how to splice, either by enhancing the splicing process or inhibiting it. The research opens the door for studying the dark matter of genes. And it helps us further understand how mutations or polymorphisms affect the functions of any gene," said study senior author, Zefeng Wang, PhD, assistant professor of pharmacology in the UNC School of Medicine and a member of UNC Lineberger Comprehensive Cancer Center.

    The study is described in a report published in the January 2013 issue of the journal Nature Structural & Molecular Biology.

  • cofty
    cofty

    I think its been said a few times in this thread that some non-coding DNA has important functions and the function of 40% of the human genome is still unknown.

    "Junk DNA" is a pejorative term that is not helpful.

    None of that changes any of the evidence presented above.

  • PSacramento
    PSacramento

    I am surprised the word is still being used, even if in quotations.

    I am sure that we will get to the point where we will understand that evertyhting has or had a purpose and there is no such a thing as "junk" anything when it comes to life.

  • cofty
    cofty

    we will understand that evertyhting has or had a purpose - PSac

    No. Have you not been reading the thread?

    We know for a certainty that 45% of the 3 billion base in your genome got there by mistake through viruses or copying errors.

    Another 40% is still to be deciphered but that 45% was not put there by any intelligent designer.

  • cofty
    cofty

    Just to clarify - that doesn't mean that some of that parasitic, non-coding DNA hasn't subsequently been put to good use or that it could now be snipped out of your genome without fatal consequences.

    The point is, we know where it originated and that it first appeared in the genome of an ancestor who was also the ancestor of other extant species.

    Still got more to write later about some specific types of parasitic DNA including SINES, LINES and Transposons.

  • PSacramento
    PSacramento
    Just to clarify - that doesn't mean that some of that parasitic, non-coding DNA hasn't subsequently been put to good use or that it could now be snipped out of your genome without fatal consequences.

    That was my point, I don't think that ANYTHING that we have is "junk".

    We may not need it anymore or perhaps it was a
    step" into the right direction, a step that needed to be taken to get to where we are now, but not "junk".

  • cofty
    cofty

    Don't ignore the word "some".

    LINES, SINES, transposons and ERVs never had a purpose. That is to look at evolution from the wrong end.

    Dawkin's metaphor of the "selfish gene" is useful in understanding why so much of our genome is parasitic.

    They serve as irrefutable proof that we were not a special creation, we descended from the same stock as the rest of the animal kingdom - and plant life too in fact.

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