Apog: Signing our DNA would indicate that someone had access to our genetic code a long time ago. Of course 100% accurate detailed unambiguous fullfillment of prophecy would be significant.
But what can you say about a book that is based on ignorance of the reproductive process in animals. The Bible thought that males squirted a little person (male or female) into the womb and that the woman was merely soil in which the seed grew. Women were fertile or infertile and had no genetic influence on offspring. They had no knowledge of female "eggs".