cantleave

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Posts by cantleave

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  6

  "Macroevolution" - where did the term come from? (Calling Coftey, et. al.)

  by cappytan in

  1. jw
  2. experiences

  is macroevolution a word made up by evolutionary scientists and darwinists, or did creationists come up with that word?.

  because, from my understanding, there is no such thing as macroevolution.

  an ape didn't give birth to a human, for instance.

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  cantleave

  Very much a creationist term!! Evolution is a continuum there is no such thing as micro and macro evolution.
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  32

  New Watchtower-- the End is coming in our lifetime again now??

  by FusionTheism in

  1. watchtower
  2. bible

  they just posted the simplified august study watchtower on jw.org.. paragraph 11 of the "expectation!

  " article says this:.

  "so even if we feel that we have been waiting a long time, this does not mean that the end is far away or that it is not coming in our lifetime.".

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  cantleave

  I was never meant to start school / leave school / get married / have children / reach middle age .........before the new system. Just old age, grand children and death to look forward to before Jokehoover strikes!!!
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  13

  It's 2015 already

  by Doltologist in

  1. jw
  2. experiences

  it's 2015. isn't it about time man stopped believing in all of this illogical and superstitious nonsense i.e.

  belief in god?.

  isn't it time we grew up?.

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  cantleave

  Man has polluted this planet to the point where it may not recover and Man, as a species, may perish.

  It's funny that Christian fundamentalism and climate change denial seem to go hand in hand..........
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  40

  What is Your Brainwashing IQ ? Take the Quiz

  by Finkelstein in

  1. watchtower
  2. beliefs

  so how much do you understand about brainwashing, its application and effects ?

  essentially lures people into its grasps and then brainwashes them for exploitation and manipulative purposes by using mental indoctrination techniques.. here's a quick quiz to take to answer some of these questions.

  http://voicesfordignity.com/brainwashing-iq/.

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  cantleave

  Very interesting quiz, reposted to Facebook. 19/21
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  7

  Are Yeast and Humans Related? - Indeed they are.......

  by cantleave in

  1. social
  2. current

  ok - this is an incredible study which shows that despite over a billion years of divergence compatible genes in two very different organisms perform similar functions.

  http://www.the-scientist.com//?articles.view/articleno/43043/title/human-genes-can-save-yeast/.

  text reads.

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  cantleave

  IMHO trying to short-circuit the search for origins by limiting choices to the petty pretend gods

  I agree, the belief in gods results in a stagnation of progress and a promulgation of ignorance. Exorcising the notion of gods and the supernatural and investing in scientific endeavour is the path to create the technology that has enables us to live longer than ever before with an ever increasing quality of life.
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  7

  Are Yeast and Humans Related? - Indeed they are.......

  by cantleave in

  1. social
  2. current

  ok - this is an incredible study which shows that despite over a billion years of divergence compatible genes in two very different organisms perform similar functions.

  http://www.the-scientist.com//?articles.view/articleno/43043/title/human-genes-can-save-yeast/.

  text reads.

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  cantleave

  so let me get this right: even after all that time, the same life process, memory, still functions after the original abiogenesis? and it worked well without us? and we discovered/confirmed that now? what clever discoverers we are!

  Indeed, and dare I say it - all of us including the deluded god squad will benefit from these discoveries. Praise Allah / Yahweh / Thor etc...
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  7

  Are Yeast and Humans Related? - Indeed they are.......

  by cantleave in

  1. social
  2. current

  ok - this is an incredible study which shows that despite over a billion years of divergence compatible genes in two very different organisms perform similar functions.

  http://www.the-scientist.com//?articles.view/articleno/43043/title/human-genes-can-save-yeast/.

  text reads.

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  cantleave

  Cofty - Approximately a third of the yeast cell's genes have a human counterpart and this study shows that even after a billion years of independent evolution these genes can still be swapped between both organisms.

  The benefit of this work will be to identify how mutations affect health. Scientists will be able to insert mutated genes into yeast and determine whether the gene is related to a disorder and then hopefully develop drugs to combat it. Brilliant stuff!

  Shame the bible didn't point the way for this - even a little hint from the almighty would have been nice.
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  7

  Are Yeast and Humans Related? - Indeed they are.......

  by cantleave in

  1. social
  2. current

  ok - this is an incredible study which shows that despite over a billion years of divergence compatible genes in two very different organisms perform similar functions.

  http://www.the-scientist.com//?articles.view/articleno/43043/title/human-genes-can-save-yeast/.

  text reads.

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  cantleave

  OK - This is an incredible study which shows that despite over a billion years of divergence compatible genes in two very different organisms perform similar functions.

  http://www.the-scientist.com//?articles.view/articleNo/43043/title/Human-Genes-Can-Save-Yeast/

  Text Reads

  large number of human genes can substitute for their defective counterparts in yeast and prevent the microorganisms from dying, according to a paper published today (May 21) in Science. Of more than 400 human-to-yeast gene replacements performed, almost 50 percent were effective at compensating for a missing vital function.

  “No one has carried out an evolutionary study of this kind before and certainly not of this scale,” saidNevan Krogan of the University of California, San Francisco, who was not involved in the work. “It’s rather satisfying to see that half of the genes could complement [the yeast function] because it justifies continuing working in yeast as a model . . . to help understand human genes.”

  Bakers’ yeast (Saccharomyces cerevisiae) shared a common ancestor with humans about a billion years ago. And this relationship, albeit distant, means that “when we read the DNA and look at their genomes we can recognize many equivalences,” said molecular biologist Edward Marcotte of the University of Texas at Austin who led the new study. “In fact, there are thousands of genes shared between humans and yeast.”

  These shared genes may appear similar, but Marcotte wanted to put them to the test, asking: “Are they swappable?” That is, could the gene encoding a human protein replace the corresponding gene in a yeast cell? Such experiments have been performed for a number of individual genes, but a large-scale, systematic approach had been lacking. “We wanted to test it for as many genes as we could feasibly do,” Marcotte said.

  The team chose test genes based on two criteria: that the yeast version of the gene was present in a single copy and that it served a function critical to cell survival. Using yeast strains in which these critical genes could be turned off at will, the team tested whether transfer of the equivalent, or orthologous, human gene could save the yeast from death.

  Forty-three percent of the 414 gene replacements the team performed could indeed rescue the yeasts’ growth defects. Incorporating data from previously reported substitution experiments, that percentage rose to 47.

  The team went on to examine whether the pairs of orthologs that could be successfully swapped had any common characteristics. Highly similar protein pairs (sharing more than 50 percent of their amino acid sequences) were more likely to be swappable. However, for orthologous pairs in the middle range (20 percent to 50 percent shared amino acid sequence), the degree of similarity had no influence. “That was quite surprising,” said Marcotte, “because we just assumed that the more similar they were, the more likely they would be to replace [function].”

  Instead, the most predictive factor for a pair’s ability to swap was whether other genes in the same pathway or complex were also swappable. For example, the sets of genes involved in sterol biosynthesis and in the proteasome complex—the cell’s garbage disposal—were almost all replaceable, but the sets of genes involved in DNA replication and repair mostly were not.

  It appears that if a process as a whole has diverged between yeast and humans, then its proteins “have all changed together,” said Madan Babu of the Medical Research Council Laboratory of Molecular Biology in the U.K., who was not involved in the work. “If you can’t replace some of the subunits of the DNA repair machinery, then you can’t replace any of them.”

  The results could have implications for medical research, said Babu. For example, “in the human population you have many individuals that carry single nucleotide polymorphisms and it is almost impossible to test what is the effect of these [on the protein],” he said. But, if the protein can be swapped into yeast cells, then “I could put in a hundred different variants of the human ortholog and, for example, I could rapidly screen whether they are sensitive to the presence of this or that drug.”

  “Those are the kind of experiments that this study now tells us are conceptually possible,” he added.

  A.H. Kachroo et al., “Systematic humanization of yeast genes reveals conserved functions and genetic modularity,” Science, 348:921-25, 2015.
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  73

  God's Spirit

  by Hold Me-Thrill Me in

  1. jw
  2. friends

  what is god's spirit?

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  i ask this of those who believe in god.

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  cantleave

  A Christmas wine hamper?

  
  
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  29

  Getting married when you are spiritually out

  by 1tMakesNoSence in

  1. social
  2. relationships

  i met this amazing girl about 6years ago at my local congregation.

  i was 100% in back then.

  about 3years ago i woke up spiritually and kept it undercover till a few months ago.. this girl is still very in (but she doesnt really do the things a reaaal jw should do.

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  cantleave

  Does she know your are mentally out? If not, do you believe that is a solid foundation for a marriage? IMO you can not enter into a life long commitment on a foundation of deception and dishonesty.