"I love you" - "I know" - Star Wars
"Snakes, I hate snakes" - Indian Jones
"I have been and always will be your friend" Star Trek Wrath of Khan
"Double dumb ass on you" Star Trek Voyage Home
"I was born in Iowa, I just work in space" Star Trek Voyage Home
"This isnt just a moonburn you know" Close Encounters.
Just some on the lighter side off the top of my head, I am too depressed to want to think of serious quotes.