I think I'd keep your conversation restricted to your disagreement with the org issues, if she's genuinely looking for help herself with doubts that will help her. I wouldnt impart any details about your personal life because as others have said she might be looking to gossip, and be using her friendship with your boss to access you which she could then maybe explain away as accidental. I think the way you handled her last time was impressive and I reckon you'll be fine ...speak your mind....
Loz x