We can't exchange one oversimplification for another. The newest science recognizing the role of insulin resistance is changing the picture but there are many other aspects to factor in. The role of genetics is huge. Familial high cholesterol and cancer risk increase from inflammation causing foods (omega 6) and HAs and PAHs from grilling must not be dismissed as myth. Kidney disease, colitis, food sensitivities, EPA limits to eating of fish from polluted water, etc.
Even eating what is generally held to be good food has risks, eating a lot of spinach (sorry Popeye) or squash or tree nuts for examples, has been associated with a slew of health issues. Most everything we could eat has some toxins or risk. That is how vegetable and animal life evolved, nothing is concerned about keeping us healthy. Bodies have needs and those needs outweigh the risks of unwanted compounds in the organisms we consume. We now through science have the ability to quantify those risks.
In short, moderate exercise, eat your vegies in moderation, eat less red meat, limit sugars and fast once in a while for 12hrs or more seems a middle road that is hard to find fault with.