Is that the hundreds of millions of followers of Islam and Jews, with their centuries old tradition of circumcision? - although that is the case, I don't think that's what Simon was referring to here.
I'm fairly sure that what Simon was referring to was gender swap clinics putting children on puberty blockers, pumping them full of cross-sex hormones, and putting chest-binders on young girls because they don't like their breasts.
Shit like that.