Verses 30 and 31 of Proverbs 8 are so apt as description of Jesus that, if you believe in Jesus and believe in the Bible, then it’s difficult to avoid the conclusion that this is meant (inspired) to be taken as a reference to Jesus.
30 then I was beside him, like a master worker; (or little child)
and I was daily his delight,
rejoicing before him always,
31 rejoicing in his inhabited world
and delighting in the human race.
No, it's not difficult to not apply this passage to Jesus.
1.) This passage is never directly quoted and referenced to Jesus in the New Testament.
2.) It is easily and naturally explained simply as a personification of an attribute of God in its original context.
Do you interpret Proverbs 1:20-21 as a reference to Jesus?
20 Wisdom crieth without; she uttereth her voice in the streets:
21 She crieth in the chief place of concourse, in the openings of the gates: in the city she uttereth her words, saying,
22 How long, ye simple ones, will ye love simplicity? and the scorners delight in their scorning, and fools hate knowledge?
How about 8:1-12?
1 Doth not wisdom cry? and understanding put forth her voice?
2 She standeth in the top of high places, by the way in the places of the paths.
3 She crieth at the gates, at the entry of the city, at the coming in at the doors.
4 Unto you, O men, I call; and my voice is to the sons of man.
5 O ye simple, understand wisdom: and, ye fools, be ye of an understanding heart.
6 Hear; for I will speak of excellent things; and the opening of my lips shall be right things.
7 For my mouth shall speak truth; and wickedness is an abomination to my lips.
8 All the words of my mouth are in righteousness; there is nothing froward or perverse in them.
9 They are all plain to him that understandeth, and right to them that find knowledge.
10 Receive my instruction, and not silver; and knowledge rather than choice gold.
11 For wisdom is better than rubies; and all the things that may be desired are not to be compared to it.
12 I wisdom dwell with prudence, and find out knowledge of witty inventions.