Rod... have you read Thomas Kuhn's The Nature of Scientific Revolutions? It's an excellent (albeit very densely written) book, and is right on point to your initial post.
Kuhn points out that all scientists (at least the practitioners of mature sciences) work within a paradigm. This paradigm can easily be dismissed as "bias", "tunnel vision", etc. But the use of a paradigm is necesssary for science to advance. Without a paradigm, it's difficult to even define useful questions or experiments, let alone interpret the results. Without a paradigm, scientists spend a lot of time arguing over basic methodologies and premises, instead of gaining new knowledge.
So unless a paradigm is falling apart, scientists tend to dismiss any work outside the paradigm, and rightly so. It's as if a construction crew is busy working on a building, and when they are halfway through, one worker says: "Let's just scrap this building and start a new one!" It's a major waste of effort.
Progress in science--even new paradigms--comes from people who are wrestling with the existing problems and paradigms of their field, not from lone "geniuses" who ignore the wisdom of the entire scientific community.
Granted, I'm sure there are some very bright and talented scientists who lose out on the game of grants and financial support. There's a large measure of luck--and undoubtedly political savvy--involved. But when I meet some lone outlier who believes that they're right and the entire scientific community is wrong, my first thought is not that they have been "criticized, ridiculed, branded, even expunged from their little academic club" to maintain the status quo. I find it far more likely that they're simply wrong.