So the lowest number I have seen proposed by credible science has been 50,000 years but the same scientists upped the top end to 500,000 years. Mitochondrial Eve (ME) is still a pretty new theory so we will see how it plays out. Please remember that the time of the aboriginal population of Australia seems to be 30,000 years ago (this was used as one of the statistical samples in the original ME dating study) and appears to have general acceptance among anthropologists. Either way its a massively long way off from the flood occurring 4,300 years ago.
How are these dates calculated? It has been my experience that dates such as these are calculated based on the evolutionary assumptions that humans and chimpanzees shared a common ancestor (the assumption of evolution) and that this ancestor lived around 4.5 million years ago. Dates based on evolutionary assumptions may be useful in trying to determine how long ago evolutionary events happened if evolution were known or to be true. However, dates based on evolutionary assumptions do not disprove a biblical chronology of all men being recently descended from Adam, because in this case there was no human/chimpanzee common ancestor.
A more empirical way to calculate the time of a human common ancestor for all modern men is to compare the genetic distance of modern men and then using real world studies of mutation rates (as opposed to those calculated based on the assumption of human/ chimps sharring a common ancestor).
The following is from Refuting Evolution by Jonathan Sarfati Eight printing November 1999.
"Evolutionists believed they had clear proof against the biblical account, because "Mitochondrial Eve" supposedly lived 200,000 years ago. However, recent evidence shows that mitochondrial DNA mutates far faster than previously thought. (24) If this new evidence is applied to "Mitochondrial Eve," it indicates that she would have lived only 6,000-6,500 years ago. (25) Of course, this is perfectly consistent with the biblically indicated age of the "mother of all living" (Gen. 3:20), (26) but an enigma for evolution/long age beliefs. Interestingly, there is a parallel account with males: evidence from the Y-chromosome is consistent with all people being descended from a single man. (27) The data is also consistent with a recent date for this "Y-chromosome Adam." (28)"
24. T.J. Parsons et al., "A High Observed Substitution Rate in the Human Mitochondrial DNA Control Region," Nature Genetics, 15:363-368, 1997.
25. L. Loewe and S. Scherer, "Mitochondrial Eve: The Plot Thickens," Trends in Ecology and Evolution, 12(11):422-423, 1997; A. Gibbons, "Calibrating the Mitochondrial Clock," Science, 279(5347):28-29, 1998.
26. C. Wieland, "A Shrinking Date for 'Eve,' " CEN Technicl Journal, 12(1):1-3, 1998.
27. R.L. Dorit, Hiroshi Akashi, and W. Gilbert, "Absence of Polymorphism at the ZFY Locus on the Human Y-Chromosome," Science,268(5214):1183-85, May 26,1995; perspective in the same issue by S. Paabo, "The Y-Chromosome and the Origin of All of Us (Men)," p. 1141-1142.
28. D.J. Batten, "Y-Chromosome Adam?" CEN Technical Journal, 9(2):139-140, 1995.