Smiddy, I found the solution on a Windows forum. Here it is:
I'll bold the steps, it's very simple ... Click on your start Icon at the bottom left-hand of your screen, and choose "Control Panel" to begin... then follow the bolded instructions below. It should work. When you are finished, restart. Send me a PM if it doesn't and I'll see what I can do. . xx tal
I had the same problem with an ASUS P7H55-M.No mouse/keyboard after shutdown and restart.Apparantly this is an issue with the hybrid shutdown option in Windows 10.The following workaround worked for me:You can disable Hybrid shutdown (or "fast startup", as it is called in Win 10) via Control Panel:
- open "Power Options"
- open "Choose what the power buttons do"
- click on "Change settings that are currently unavailable"
- uncheck "Turn on fast startup"
From now on Win 10 will initialize all driver on startup. This will take longer but it works.