I certainly do not believe that any particular place on Earth should be considered "Holy", i.e The temple Mount in Jerusalem.
Yes, certain Sites should be safeguarded as part of the heritage of all humans, but not made "Holy" by one group to the exclusion of others.
"Holy" books are a joke too, they are all written by men. Again, preserve them for posterity, but don't make a fetish of them.
Having said that, some people give off an air of "holiness" or "sainthood" or whatever you wish to call it. Often such people are not religious, they just have that quality. They are intrinsically holy in themselves.
They are also extremely rare.